Image and Video Gallery

This is a searchable collection of scientific photos, illustrations, and videos. The images and videos in this gallery are licensed under Creative Commons Attribution Non-Commercial ShareAlike 3.0. This license lets you remix, tweak, and build upon this work non-commercially, as long as you credit and license your new creations under identical terms.

Precisely Delivering Chemical Cargo to Cells

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Moving protein or other molecules to specific cells to treat or examine them has been a major biological challenge. Nature Nanotechnology View Media

Cas4 nuclease protein structure

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This wreath represents the molecular structure of a protein, Cas4, which is part of a system, known as CRISPR, that bacteria use to protect themselves against viral invaders. Fred Dyda, NIDDK View Media

Active Site of E. coli response regulator PhoB

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Active site of E. coli response regulator PhoB. Ann Stock, Rutgers University View Media

Bioluminescent imaging in adult zebrafish - lateral view

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Luciferase-based imaging enables visualization and quantification of internal organs and transplanted cells in live adult zebrafish. Kenneth Poss, Duke University View Media

Plasma membrane (with labels)

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The plasma membrane is a cell's protective barrier. See image 2523 for an unlabeled version of this illustration. Featured in The Chemistry of Health. Crabtree + Company View Media

Chang Shan

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For thousands of years, Chinese herbalists have treated malaria using Chang Shan, a root extract from a type of hydrangea that grows in Tibet and Nepal. Paul Schimmel Lab, Scripps Research Institute View Media

Molecular view of glutamatergic synapse

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This illustration highlights spherical pre-synaptic vesicles that carry the neurotransmitter glutamate. Amy Wu and Christine Zardecki, RCSB Protein Data Bank. View Media

Diversity oriented synthesis: generating skeletal diversity using folding processes

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This 1 1/2-minute video animation was produced for chemical biologist Stuart Schreiber's lab page. The animation shows how diverse chemical structures can be produced in the lab. Eric Keller View Media

A drug's life in the body (with labels)

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A drug's life in the body. Medicines taken by mouth (oral) pass through the liver before they are absorbed into the bloodstream. Crabtree + Company View Media

Bioluminescent imaging in adult zebrafish - lateral and overhead view

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Luciferase-based imaging enables visualization and quantification of internal organs and transplanted cells in live adult zebrafish. Kenneth Poss, Duke University View Media

Plastic-eating enzymes

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PETase enzyme degrades polyester plastic (polyethylene terephthalate, or PET) into monohydroxyethyl terephthalate (MHET). Amy Wu and Christine Zardecki, RCSB Protein Data Bank. View Media

Cascade reaction promoted by water

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This illustration of an epoxide-opening cascade promoted by water emulates the proposed biosynthesis of some of the Red Tide toxins. Tim Jamison, Massachusetts Institute of Technology View Media

Anti-tumor drug ecteinascidin 743 (ET-743), structure without hydrogens 01

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Ecteinascidin 743 (ET-743, brand name Yondelis), was discovered and isolated from a sea squirt, Ecteinascidia turbinata, by NIGMS grantee Kenneth Rinehart at the University of Illinois. Timothy Jamison, Massachusetts Institute of Technology View Media

X-ray co-crystal structure of Src kinase bound to a DNA-templated macrocycle inhibitor 4

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X-ray co-crystal structure of Src kinase bound to a DNA-templated macrocycle inhibitor. Markus A. Seeliger, Stony Brook University Medical School and David R. Liu, Harvard University View Media

X-ray co-crystal structure of Src kinase bound to a DNA-templated macrocycle inhibitor 1

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X-ray co-crystal structure of Src kinase bound to a DNA-templated macrocycle inhibitor. Markus A. Seeliger, Stony Brook University Medical School and David R. Liu, Harvard University View Media

CCP enzyme

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The enzyme CCP is found in the mitochondria of baker’s yeast. Scientists study the chemical reactions that CCP triggers, which involve a water molecule, iron, and oxygen. Protein Data Bank. View Media

Master clock of the mouse brain

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An image of the area of the mouse brain that serves as the 'master clock,' which houses the brain's time-keeping neurons. The nuclei of the clock cells are shown in blue. Erik Herzog, Washington University in St. Louis View Media

Anti-tumor drug ecteinascidin 743 (ET-743), structure without hydrogens 03

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Anti-tumor drug ecteinascidin 743 (ET-743), structure without hydrogens 04

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White Poppy

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A white poppy. View cropped image of a poppy here 3423. Judy Coyle, Donald Danforth Plant Science Center View Media

Nucleolus subcompartments spontaneously self-assemble 2

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The nucleolus is a small but very important protein complex located in the cell's nucleus. Nilesh Vaidya, Princeton University View Media

Insulin production and fat sensing in fruit flies

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Fourteen neurons (magenta) in the adult Drosophila brain produce insulin, and fat tissue sends packets of lipids to the brain via the lipoprotein carriers (green). Akhila Rajan, Fred Hutchinson Cancer Center View Media

Atomic-level structure of the HIV capsid

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This animation shows atoms of the HIV capsid, the shell that encloses the virus's genetic material. Juan R. Perilla and the Theoretical and Computational Biophysics Group, University of Illinois at Urbana-Champaign View Media

O2 reacting with a flavin-dependent enzyme

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Department of Biological Chemistry, University of Michigan View Media

Enzyme transition states

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The molecule on the left is an electrostatic potential map of the van der Waals surface of the transition state for human purine nucleoside phosphorylase. Vern Schramm, Albert Einstein College of Medicine of Yeshiva University View Media

In vitro assembly of a cell-signaling pathway

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T cells are white blood cells that are important in defending the body against bacteria, viruses and other pathogens. Xiaolei Su, HHMI Whitman Center of the Marine Biological Laboratory View Media

Genetically identical mycobacteria respond differently to antibiotic 1

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Antibiotic resistance in microbes is a serious health concern. So researchers have turned their attention to how bacteria undo the action of some antibiotics. Bree Aldridge, Tufts University View Media

Nucleolus subcompartments spontaneously self-assemble 1

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The nucleolus is a small but very important protein complex located in the cell's nucleus. Nilesh Vaidya, Princeton University View Media

Network Map

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This network map shows the overlap (green) between the long QT syndrome (yellow) and epilepsy (blue) protein-interaction neighborhoods located within the human interactome. Seth Berger, Mount Sinai School of Medicine View Media

Carbon building blocks (with examples)

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The arrangement of identical molecular components can make a dramatic difference. For example, carbon atoms can be arranged into dull graphite (left) or sparkly diamonds (right). Crabtree + Company View Media

Dynein moving along microtubules

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Dynein (green) is a motor protein that “walks” along microtubules (red, part of the cytoskeleton) and carries its cargo along with it. This video was captured through fluorescence microscopy. Morgan DeSantis, University of Michigan. View Media

Fruit fly brain responds to adipokines

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Drosophila adult brain showing that an adipokine (fat hormone) generates a response from neurons (aqua) and regulates insulin-producing neurons (red).
Akhila Rajan, Fred Hutchinson Cancer Center View Media

Himastatin

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A model of the molecule himastatin, which was first isolated from the bacterium Streptomyces himastatinicus. Himastatin shows antibiotic activity. Mohammad Movassaghi, Massachusetts Institute of Technology. View Media

Antibodies in silica honeycomb

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Antibodies are among the most promising therapies for certain forms of cancer, but patients must take them intravenously, exposing healthy tissues to the drug and increasing the risk of side effects. Chenghong Lei, Pacific Northwest National Laboratory & Karl Erik Hellstrom, University of Washington View Media

Computer algorithm

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This computer algorithm plots all feasible small carbon-based molecules as though they were cities on a map and identifies huge, unexplored spaces that may help fuel research into new drug therapies. Aaron Virshup, Julia Contreras-Garcia, Peter Wipf, Weitao Yang and David Beratan, University of Pittsburgh Center for Chemical Methodologies and Library Development View Media

X-ray co-crystal structure of Src kinase bound to a DNA-templated macrocycle inhibitor 6

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X-ray co-crystal structure of Src kinase bound to a DNA-templated macrocycle inhibitor. Markus A. Seeliger, Stony Brook University Medical School and David R. Liu, Harvard University View Media

Circadian rhythms and the SCN

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Circadian rhythms are physical, mental, and behavioral changes that follow a 24-hour cycle. NIGMS View Media

Movie of in vitro assembly of a cell-signaling pathway

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T cells are white blood cells that are important in defending the body against bacteria, viruses and other pathogens. Xiaolei Su, HHMI Whitman Center of the Marine Biological Laboratory View Media

Crystals of CCD-1 in complex with cefotaxime

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CCD-1 is an enzyme produced by the bacterium Clostridioides difficile that helps it resist antibiotics. Keith Hodgson, Stanford University. View Media

Bacillus anthracis being killed

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Bacillus anthracis (anthrax) cells being killed by a fluorescent trans-translation inhibitor, which disrupts bacterial protein synthesis. John Alumasa, Keiler Laboratory, Pennsylvania State University View Media

Human opioid receptor structure superimposed on poppy

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Opioid receptors on the surfaces of brain cells are involved in pleasure, pain, addiction, depression, psychosis, and other conditions. Raymond Stevens, The Scripps Research Institute View Media

See how immune cell acid destroys bacterial proteins

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This animation shows the effect of exposure to hypochlorous acid, which is found in certain types of immune cells, on bacterial proteins. American Chemistry Council View Media

Anti-tumor drug ecteinascidin 743 (ET-743) with hydrogens 02

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Brain waves of a patient anesthetized with propofol

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A representation of a patient’s brain waves after receiving the anesthetic propofol. Emery N. Brown, M.D., Ph.D., Massachusetts General Hospital/Harvard Medical School, Picower Institute for Learning and Memory, and Massachusetts Institute of Technology. View Media

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